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ADMET-1 Conference 2004
San Diego, CA, USA
February 11 - 13, 2004
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Workshop
| Title: | Strategies and tactics for achieving potency and exposure |
| Presenter: | Rob DeWitte |
| Date: | Thursday, February 12, 2004 from 1:00 PM - 2:00 PM |
| Location: | Gold West Room |
| Abstract: | Finding a new drug is even more complicated than validating a target and optimizing the potency of the lead compound. Until the availability of larger samples (>~100mg) and animal data, the medicinal chemist has little input about the aspects of his/her molecules that influence exposure at the site of action. This talk explores the physical basis of many of the in vivo barriers between dose and exposure and provides a set of rational working hypotheses that may assist drug discovery projects to bring forward promising candidates more quickly. |
ACD/Labs' Poster Schedule
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This page was last updated
12 September 2007
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